Max Nieuwdorp has written a book “We are our hormones”
Added on 10 oktober 2022Why do we react so violently to an exciting situation? Why do men and women become more similar as they get older? And why do older people need more salty food?
Influence of the microbiome, diet and genetics on inter-individual variation in the human plasma metabolome
Added on 10 oktober 2022The levels of the thousands of metabolites in the human plasma metabolome are strongly influenced by an individual’s genetics and the composition of their diet and gut microbiome. Here, by assessing 1,183 plasma metabolites in 1,368 extensively phenotyped individuals from the Lifelines DEEP and Genome of the Netherlands cohorts, we quantified the proportion of inter-individual variation in the plasma metabolome explained by different factors, characterizing 610, 85 and 38 metabolites as dominantly associated with diet, the gut microbiome and genetics, respectively.
Cover story in the September 2022 issue of Nature Cardiovascular Research
Added on 28 september 2022Our results suggest that sex-dependent ageing may underlie the differences between the sexes in CMDs, which highlights the importance of accounting for both age and sex when assessing an individual’s risk of developing CMD. Future large longitudinal studies (including follow-up of this cohort) will be crucial for link the age dynamics of sex differences in these risk factors to the long-term effect on diseases and to provide options for early disease prevention
The Marten Hofker Talent Program 2021
In the new program, three fellowships (max € 80.000) of 1 year for talented postdocs, equally distributed across the three partners (AmsterdamUMC, UMCGroningen, Radboudumc) will be funded. The fellowships will strongly be connected to the research aims of IN CONTROL II and specifically aim to either broaden the scope and impact of the specific objectives of IN CONTROL II and/or to accelerate translation towards patient care
Jingyuan Fu has been awarded ERC-Consolidator Grant (2 million) and NWO-Vici grant (1.5 million) in 2021
Jingyuan Fu has been awarded ERC-Consolidator Grant (2 million) and NWO-Vici grant (1.5 million) in 2021
Daria Zhernakova was awarded a Veni grant to study gender differences in the cardiometabolic syndrome (250K Euro)
Daria Zhernakova was awarded a Veni grant to study gender differences in the cardiometabolic syndrome (250K Euro).
Sasha Zhernakova is partner in an awarded Gravitation grant (Exposome-NL; 17.4 M Euro)
Sasha Zhernakova is partner in an awarded Gravitation grant (Exposome-NL; 17.4 M Euro)
Researchers from IN CONTROL II have been involved in the publication of the protocols best used to investigate trained immunity in vitro
Researchers from IN CONTROL II have been involved in the publication of the protocols best used to investigate trained immunity in vitro (Dominguez-Andres…., Riksen, Joosten, Netea. STAR protocols 2021; https://doi.org/10.1016/j.xpro.2021.100365).