Publications

  1. Innate immune cell activation and epigenetic remodeling in symptomatic and asymptomatic atherosclerosis in humans in vivo. Siroon Bekkering, Inge van den Munckhof, Tim Nielen, Joost Rutten, Evert Lamfers, Jacqueline de Graaf, Leo AB Joosten, Mihai G Netea, Marc ER Gomes, Niels P Riksen – Atherosclerosis. 2016 Nov;254:228-236.
  2. Sex differences in fat distribution influence the association between body mass index and arterial stiffness. Inge C.L. van den Munckhof, Suzanne Holewijn, Jacqueline de Graaf, Joost H.W. Rutten – J Hypertens 2017, Jun;35(6):1219-1225.
  3. Relation between age and carotid artery intima-medial thickness: a systematic review. Inge CL van den Munckhof, Helen Jones, Maria TE Hopman, Jacqueline de Graaf, Jean Nyakayiru, Bart van Dijk, Thijs MH Eijsvogels, Dick HJ Thijssen. Accepted.
  4. Relation between age and carotid artery intima-medial thickness: a systematic review. Clin Cardiol. 2018 May. https://www.ncbi.nlm.nih.gov/pubmed/?term=3.Relation+between+age+and+carotid+artery+intima-medial+thickness%3A+a+systematic+review
  5. Role of the gut microbiota in chronic low-grade inflammation as driver for cardiovascular disease: a systematic review on human studies. Inge van den Munckhof, …, Joost Rutten.
  6. Physiological and genetic adaptations to diving in sea nomads. Ilardo MA, Moltke I, Korneliussen TS, Cheng J, Stern AJ, Racimo F, de Barros Damgaard P, Sikora M, Seguin-Orlando A, Rasmussen S, van den Munckhof ICL, Ter Horst R, Joosten LAB, Netea MG, Salingkat S, Nielsen R, Willerslev E. Cell. 2018 Apr. Is published. https://www.ncbi.nlm.nih.gov/pubmed/?term=Physiological+and+genetic+adaptations+to+diving+in+sea+nomads
  7. Direct binding to free fatty acid decreases plasma magnesium in hypertriglyceridemic states. Steef Kurstjens; Jeroen de Baaij; Caro Overmars-Bos; Inge van den Munckhof; Veronica Garzero; Marijke de Vries; Benjamin Burggraaf; Janna van Diepen; Niels Riksen; Joost Rutten; Mihai Netea; Manuel Castro Cabezas; René Bindels; Frances Ashcroft; Cees Tack; Joost Hoenderop. Submitted to Translational Research.
  8. A role for TLR10 in obesity and adipose tissue morphology. Cytokine. 2018 Aug. Lily Boutens, Andreea-Manuela Mirea, Inge van den Munckhof,  Marije Oosting, Martin Jaeger, Anneke Hijmans, Mihai G. Netea, Leo A.B.Joosten, Rinke Stienstra. https://www.ncbi.nlm.nih.gov/pubmed/?term=A+role+for+TLR10+in+obesity+and+adipose+tissue+morphology
  9. Cardiovasc Res. 2018 Jun 1;114(7):944-953. doi: 10.1093/cvr/cvy092. The mineralocorticoid receptor as a modulator of innate immunity and atherosclerosis.van der Heijden CDCC1, Deinum J1, Joosten LAB1, Netea MG1,2, Riksen NP1.
  10. Circ Res. 2018 Mar 2;122(5):664-669. doi: 10.1161/CIRCRESAHA.117.312465. Epub 2018 Jan 24. Trained Innate Immunity as a Novel Mechanism Linking Infection and the Development of Atherosclerosis. Leentjens J1, Bekkering S1, Joosten LAB1, Netea MG1, Burgner DP1, Riksen NP2.
  11. Cell. 2018 Jan 11;172(1-2):135-146.e9. doi: 10.1016/j.cell.2017.11.025. Metabolic Induction of Trained Immunity through the Mevalonate Pathway. Bekkering S1, Arts RJW2, Novakovic B3, Kourtzelis I4, van der Heijden CDCC2, Li Y5, Popa CD6, Ter Horst R2, van Tuijl J2, Netea-Maier RT7, van de Veerdonk FL2, Chavakis T4, Joosten LAB8, van der Meer JWM2, Stunnenberg H3, Riksen NP9, Netea MG10.
  12. Cell. 2018 Jan 11;172(1-2):162-175.e14. doi: 10.1016/j.cell.2017.12.013. Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming. Christ A1, Günther P2, Lauterbach MAR3, Duewell P4, Biswas D5, Pelka K6, Scholz CJ2, Oosting M7, Haendler K2, Baßler K2, Klee K2, Schulte-Schrepping J2, Ulas T2, Moorlag SJCFM7, Kumar V8, Park MH9, Joosten LAB7, Groh LA7, Riksen NP7, Espevik T10, Schlitzer A2, Li Y8, Fitzgerald ML11, Netea MG12, Schultze JL13, Latz E14 . 

Invited Lectures


June2018
Gordon conference over ‘Epigenomics in diabetes and other metabolic disorders’, Hong Kong (Niels Riksen) 

 

To submit (collaboration with WP2/WP4):

  1. IL-18 pathway modulates lipoprotein metabolism in obesity-related atherosclerosis. Inge van den Munckhof, Rob ter Horst …, Mihai Netea. Submit to Plos Medicine
  2. Microbial impact on circulating level of glycoprotein-N-acetyls is linked to liver fat and vascular disease. Alexander Kurilshikov, PhD; Inge CL van den Munckhof,, Marc J Bonder, MSc; Kiki Schraa, Joost HW Rutten, Niels P Riksen, Jacqueline de Graaf, Marije Oosting, PhD; Leo A B Joosten, PhD; Debby Koonen, PhD, LifeLines-DEEP cohort Study; BBMRI Metabolomics Consortium; P Eline Slagboom, PhD; Ramnik J Xavier,PhD; Folkert Kuipers, PhD; Marten H Hofker, PhD; Cisca Wijmenga, PhD; Mihai G Netea, PhD; Alexandra Zhernakova, PhD; Jingyuan Fu, PhD. Submit to Plos Medicine
  3. The association between hepatic steatosis and the volume of superficial versus deep subcutaneous adipose tissue. A study in overweight subjects across the spectrum of the metabolic syndrome. Tessa Brand, Inge CL van den Munckhof, Marinette van der Graaf, Jacqueline de Graaf, Joost HW Rutten.